Upon loading up the level, the game generates a few missions for the player to complete: upon failure or success of all of these missions, the game allows the player to head to the next floor. While there is permadeath, the layout of the game is very unusual by the standards of traditional roguelikes.
The game is billed as a cross between roguelikes and Immersive Sim games, such as Deus Ex. The player can use explosives, burn down buildings, flood air vents with poison gas, shoot up both banks and drug dens, and generally cause ridiculous amounts of chaos in an urban environment. In practice, procedural mayhem and wanton death is more likely to ensure. Streets of Rogue is a real-time Roguelike-ish PC game set in a Wretched Hive of a city filled with crooks and governed by a corrupt mayor the player, an agent of the The Resistance, is sent to climb the city and assassinate him.